What negative outcome was noted in a clinical trial involving individuals with schizophrenia supplementing with mangosteen rind over 24 weeks?
Answer
Worsened symptom severity
While mangosteen extracts show benefits in other areas, research context matters significantly, as demonstrated by a specific clinical trial involving individuals diagnosed with schizophrenia. When these participants were given supplements containing mangosteen rind over a 24-week period, the results contradicted potential therapeutic expectations. Instead of improvement, the trial observed a negative impact, specifically reporting that the symptom severity for the condition worsened over the course of the study. This finding underscores the caution that plant extracts are not universally beneficial and that their effects can be highly dependent on the specific population and underlying health condition.
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