Concentrated mangosteen products raise a prominent safety caution regarding which physiological process?
Answer
Slowing down blood coagulation by inhibiting platelet aggregation
A significant clinical safety consideration associated with concentrated preparations of mangosteen, particularly those high in xanthones, involves the circulatory system. These compounds possess the capability to inhibit platelet aggregation, which is the necessary first step in the blood clotting cascade. Consequently, this action slows down the overall process of blood coagulation. This interaction presents a direct risk for individuals already taking anticoagulant medications, such as warfarin, or those suffering from pre-existing blood clotting disorders, as it elevates the potential for excessive bruising or bleeding.
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