What severe adverse effect is specifically associated with extremely high Vitamin C intake in individuals diagnosed with G6PD Deficiency?

Answer

Hemolysis, which is the destruction of red blood cells

Certain pre-existing genetic conditions make individuals particularly vulnerable to the concentrated pharmacological effects of mega-dosing Vitamin C found in potent acerola products. A condition demanding special attention is Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency, an enzyme disorder. When individuals with this specific genetic disorder consume extremely high quantities of Vitamin C, there is a recognized risk that this massive intake can trigger a cascade leading to hemolysis. Hemolysis is the pathological process wherein the red blood cells break down prematurely or are destroyed, potentially leading to acute hemolytic anemia and associated complications.

What severe adverse effect is specifically associated with extremely high Vitamin C intake in individuals diagnosed with G6PD Deficiency?
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