Which chemical group in alfalfa must be avoided by individuals with hormone-sensitive cancers due to potential growth promotion?
Phytoestrogens
Phytoestrogens are plant compounds found in alfalfa that possess a chemical structure similar to the human hormone estrogen. This estrogen-like activity is the basis for their contraindication in certain health states. Specifically, individuals diagnosed with conditions sensitive to estrogen exposure, such as breast, uterine, or ovarian cancer, are warned against using alfalfa because it may stimulate the proliferation of these estrogen-dependent cancer cells, a risk supported by some in vitro or observational studies. This hormonal interference also applies to conditions like endometriosis or uterine fibroids. While they may offer symptomatic relief for menopausal issues, their hormonal action necessitates caution, especially in concentrated supplement forms.
