Which amino acid in alfalfa seeds is linked to inciting or worsening Systemic Lupus Erythematosus (SLE) symptoms?
Answer
L-canavanine
L-canavanine is a non-protein amino acid found within alfalfa, with concentration generally noted in the seeds or concentrated seed products. Research suggests that this specific compound possesses properties capable of stimulating or exacerbating the symptoms associated with autoimmune conditions. Systemic Lupus Erythematosus (SLE) is particularly highlighted in connection with L-canavanine consumption, to the extent that primate studies demonstrated the ability of alfalfa sprouts to induce an SLE-like syndrome. Therefore, individuals diagnosed with SLE, multiple sclerosis (MS), or rheumatoid arthritis (RA) are advised to avoid alfalfa due to the presence and effect of L-canavanine on immune activity.
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