What is the main reason defining common side effects for all Dendrobium preparations is challenging?

Answer

Vast number of species and varied processing/extraction methods

The primary difficulty in establishing generalized common side effects for Dendrobium stems from the genus encompassing a huge variety of species. Furthermore, the methods used to process or extract these species for use in modern dietary supplements vary widely. Because there is no universal benchmark for safety or efficacy across these diverse preparations, the resulting user experiences can differ substantially from one brand or preparation method to another. This variability means that observed adverse reactions might be specific to a particular species or extraction concentration rather than being a universal effect of the herb itself.

What is the main reason defining common side effects for all Dendrobium preparations is challenging?
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