What painful condition can high daily consumption of purines in sardines trigger?
Answer
Gout flare-ups due to increased uric acid production
Sardines, similar to many types of seafood, naturally contain compounds known as purines. When the human body metabolizes these purines, uric acid is produced as a byproduct. For individuals who are either genetically predisposed to gout or are actively managing high uric acid levels in their system, consuming high-purine foods like sardines on a daily basis can precipitate painful inflammatory attacks, commonly referred to as gout flare-ups. This metabolic pathway establishes a clear medical contraindication for very frequent, high-quantity consumption.
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