How do oil-based concentrates influence the dermal absorption window compared to water-based sprays?

Answer

They can remain on the skin longer, increasing the window for absorption.

The physical properties and the formulation of the pesticide significantly dictate the duration and extent of skin exposure. Water-based sprays often have the advantage that they might evaporate relatively quickly once applied or splashed onto the skin surface. However, formulations like oil-based concentrates or emulsifiable concentrates, which are often employed by professional applicators, possess characteristics that cause them to persist on the skin surface for extended periods following contact. This extended residency time directly translates to a prolonged window during which the chemical agents have the opportunity to penetrate the dermal barrier and enter the body. Consequently, the persistence of the formulation directly correlates with an increased potential for systemic absorption.

How do oil-based concentrates influence the dermal absorption window compared to water-based sprays?
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