Why are systemic cholesterol effects not typically expected solely from occasional fresh berry consumption?

The effects were observed using concentrated seed extracts, not fresh berries

There is a significant distinction between the effects seen in preclinical research and what an individual might achieve by consuming the fresh fruit casually. The potent cholesterol-lowering results, such as the 15–20% drop in Total Cholesterol observed in hamsters, were achieved using highly concentrated extracts specifically derived from the seeds, which contain high levels of triterpenoids. The whole, fresh berry contains only trace amounts of these active systemic components in the pulp portion consumed for flavor modification. Therefore, relying solely on occasional consumption of the fresh fruit is unlikely to yield the significant lipid profile changes documented in studies that utilized standardized, concentrated medicinal extracts intended to target high cholesterol directly.