When might introducing high-dose, unverified Opuntia extracts theoretically cause issues for an individual?

If the person has pre-existing liver conditions or is taking prescription medications

While whole foods derived from *Opuntia* generally present a low risk profile for healthy individuals, caution becomes necessary when shifting from whole food consumption to highly concentrated, unverified supplements. If an individual is already managing a diagnosed liver condition, their organ's capacity to process substances is already compromised. Furthermore, many prescription drugs are metabolized by the liver. Introducing a high dose of an unverified herbal extract at this stage introduces an unpredictable variable. Theoretically, such a concentrated substance could interact negatively with existing pathology or interfere with the established metabolic pathways handling prescription medications, even if the compound itself is protective at lower, dietary doses. Discussing any concentrated supplement with a hepatologist is crucial in such scenarios.