How does the toxic principle podophyllotoxin primarily affect the digestive system?
Answer
It acts as a strong purgative, causing severe gastrointestinal upset.
The primary mechanism through which podophyllotoxin exerts its harmful effects when ingested is by functioning as a potent purgative. This chemical action forces the body into a rapid and violent expulsion of its contents. Consequently, consumption leads directly to severe gastrointestinal upset characterized by immediate and intense symptoms. This powerful cathartic nature is what drives the progression toward significant fluid loss and potential dehydration if a sufficient quantity of the toxic material has been consumed.
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