Beyond nausea and vomiting, what severe outcomes can occur from consuming a large quantity of poisonous mayapple parts?

Answer

Depression of the central nervous system, leading to convulsions, coma, and potentially death.

While the initial and most common effects of ingesting poisonous parts are gastrointestinal—nausea, vomiting, pain, and diarrhea—the severity escalates considerably if a large enough dose of the toxin is consumed. When the toxic load overwhelms the body's immediate defenses, the effects progress beyond typical stomach upset to involve the central nervous system. This systemic involvement manifests as depression of the CNS, which can precipitate severe outcomes such as convulsions and coma. In the most extreme and fatal cases resulting from severe poisoning, death can tragically occur.

Beyond nausea and vomiting, what severe outcomes can occur from consuming a large quantity of poisonous mayapple parts?
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