Which specific channels does Onion Peel Extract (OPE) regulate to increase sperm motility?
Answer
Voltage-gated proton (Hv1) channels
A sophisticated finding regarding sperm health improvement relates directly to the function of Onion Peel Extract (OPE) on sperm motility. OPE has been shown to increase sperm motility by regulating the voltage-gated proton (Hv1) channels. These Hv1 channels are functionally crucial because they are responsible for the rapid extrusion of protons, a necessary physiological step for achieving and maintaining healthy sperm function and efficient movement. Furthermore, this regulation by OPE is described as being partially dependent on the involvement of protein kinase C (PKC), illustrating a specific molecular pathway through which the compounds concentrated in the peel benefit sperm performance.
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