How does onion extract potentially elevate testosterone synthesis via signaling pathways?
By leading to elevated levels of Luteinizing hormone (LH) compared to controls.
Testosterone synthesis in the Leydig cells of the testes is critically regulated by Luteinizing Hormone (LH). The mechanism supporting increased testosterone production following the administration of fresh onion juice or onion extract involves an elevation of LH levels when compared to control groups. This increased LH then acts upon the Leydig cells, signaling them to boost their regulation and subsequent production of testosterone. Additionally, the text notes that certain onion compounds may enhance the activity of 5′ AMP-activated protein kinase (AMPK), an enzyme also implicated in activating testosterone production within these specialized testicular cells, providing a secondary, complementary pathway for hormonal support.
