What lipid peroxidation marker was reduced in animal models treated with onion extract following testicular injury?
Answer
Malondialdehyde (MDA)
In animal models subjected to severe testicular injury or chemical toxicants specifically designed to induce significant oxidative stress, onion extract demonstrated a clear protective and restorative effect. This protective action was quantified by observing positive shifts in key biochemical markers associated with cellular damage. Specifically, treatment helped reduce markers of lipid peroxidation, with malondialdehyde (MDA) being explicitly cited as one such marker whose levels were lowered following onion extract administration. Concurrently, the treatment helped restore the activity of crucial antioxidant enzymes like SOD and GPx, demonstrating a comprehensive mitigation of oxidative damage at the cellular level.
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