Which class of medication, often prescribed for high blood pressure, causes kidneys to flush out more magnesium?
Answer
Diuretics
Certain pharmaceutical agents can actively accelerate the depletion of bodily magnesium stores by interfering with renal handling of the mineral. Specifically, diuretics, which are frequently prescribed to manage conditions such as high blood pressure by increasing fluid excretion, also cause the kidneys to eliminate an elevated amount of magnesium through the urine. This medication-induced mineral wasting contributes significantly to the development or exacerbation of a magnesium deficiency over time. While Proton Pump Inhibitors (PPIs) are also mentioned as affecting magnesium balance by reducing long-term absorption, diuretics directly impact excretion rates, leading to increased flushing of the mineral.

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