What systemic health effects, other than cancer, have been linked to exposure to PFAS compounds?

Answer

Altered thyroid hormone levels and changes in liver enzymes

Beyond the established concerns regarding cancer risk associated with certain legacy PFAS, scientific investigation points to broader systemic impacts resulting from exposure. Specifically, the endocrine system appears to be vulnerable, as research has demonstrated associations between PFAS exposure and alterations in normal thyroid hormone levels, which are crucial for metabolic regulation. Furthermore, the liver, as a primary organ for detoxification and processing, shows signs of stress; some studies have indicated observable changes in liver enzymes, suggesting impairment in normal hepatic function. These effects, alongside documented developmental concerns such as low birth weight, contribute to the overall understanding of PFAS toxicity beyond oncological risks.

What systemic health effects, other than cancer, have been linked to exposure to PFAS compounds?
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