What specific danger related to PAs is a concern when borage is consumed by women who are breastfeeding?

Answer

PAs present in the plant parts could potentially pass into breast milk

Borage consumption is strictly cautioned against during breastfeeding primarily due to the potential for the toxic constituents, the pyrrolizidine alkaloids (PAs), to transfer into the mother's milk. If these PAs enter the infant's system via nursing, they pose a risk of systemic toxicity. Additionally, the text notes that infant blood disorders, specifically methemoglobinemia, commonly known as blue baby syndrome, have been historically linked to the ingestion of borage purée due to its high nitrate levels, which infants lack the metabolic capability to process effectively.

What specific danger related to PAs is a concern when borage is consumed by women who are breastfeeding?
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