If kidney function is compromised, what effect does the neurotoxin caramboxin have?
Answer
It can cross the blood-brain barrier, affecting the central nervous system.
Caramboxin is described as a potent neurotoxin naturally present in star fruit. For individuals with properly functioning kidneys, this compound is typically eliminated from the body without issue. When kidney function is compromised, the inability to clear this toxin allows caramboxin to breach the blood-brain barrier. Once across this barrier, it directly impacts the central nervous system, which accounts for the neurological symptoms observed during poisoning events.
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