Which two reproductive hormones primarily orchestrate the four main menstrual cycle phases?
Answer
Estrogen and progesterone
The four conventional phases of the menstrual cycle—menstruation, follicular phase, ovulation, and the luteal phase—are fundamentally orchestrated by the fluctuating levels of two primary reproductive hormones: estrogen and progesterone. Estrogen drives the rebuilding and thickening of the uterine lining during the follicular phase and triggers the LH surge leading to ovulation. Progesterone dominates the luteal phase, responsible for maintaining the uterine lining in a thick, blood-rich state ready to support a potential pregnancy. These two hormones cycle in opposition and cooperation to manage the monthly biological preparation.

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