What specific pharmacological action does caffeine have that makes coffee and caffeinated teas reflux culprits?
Answer
Caffeine acts as a muscle relaxant, specifically relaxing the LES
Caffeine is identified as a major contributor to reflux issues because of its effect on smooth muscle tissue, particularly the lower esophageal sphincter (LES). Caffeine functions as a muscle relaxant. When this relaxation effect targets the LES, the valve designed to keep stomach contents contained loosens its grip. When the LES relaxes inappropriately or too frequently, it creates an easy pathway for stomach acid to escape upwards into the sensitive esophageal tissue, leading to heartburn symptoms.
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