Where are CB1 receptors highly concentrated, explaining cannabis's neurological impact?
Answer
In the brain and central nervous system
The concentration and location of the CB1 receptor directly correlate with the observed effects of cannabis consumption. CB1 receptors are described as being highly concentrated specifically within the brain and the central nervous system (CNS). This high density in neurological tissue is what accounts for the well-documented psychoactive and neurological effects experienced by users, such as alterations in mood, memory, coordination, and judgment. In comparison, the CB2 receptors, which are linked more closely to immune function and inflammation, are predominantly found in peripheral tissues outside the main CNS areas.
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