What toxic compounds found in raw Sambucus leaves, stems, and unripe berries can release cyanide in the digestive tract?
Answer
Cyanogenic glycosides, most notably sambunigrin
Raw or improperly processed parts of the Sambucus plant, including the leaves, stems, bark, and roots, naturally harbor chemical compounds classified as cyanogenic glycosides. The specific glycoside highlighted is sambunigrin. When these compounds are ingested in their uncooked state, digestive enzymes break them down, leading to the subsequent release of highly toxic hydrogen cyanide within the gastrointestinal system. This chemical reaction is the primary reason that uncooked elderberry components pose a significant ingestion hazard, leading to acute distress.

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