What mechanism does honey's high sugar content utilize to help create an effective barrier against infection when used topically on wounds?

Answer

It naturally draws moisture away from bacteria via the osmotic effect

Honey's traditional use in wound care is supported by several scientific principles, one of the most important being its high osmotic potential derived from its high sugar concentration. Osmosis is the process where water moves across a semipermeable membrane from an area of low solute concentration to an area of high solute concentration. Because honey has such a high concentration of sugar (around 80%), it aggressively draws water out of bacterial cells and surrounding tissues. This dehydration (osmotic effect) inhibits bacterial growth and proliferation, effectively creating an environment unfavorable for infection, alongside its slightly acidic pH and mild antiseptic action from hydrogen peroxide.

What mechanism does honey's high sugar content utilize to help create an effective barrier against infection when used topically on wounds?

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