How long should the affected area be immersed in 45°C (113°F) water following a Physalia sting?
Answer
Approximately 45 minutes
The optimal protocol for pain management after venom inactivation involves prolonged exposure to moderate heat. To effectively inactivate the toxins already injected into the skin and thereby reduce the associated pain response, the affected area should be immersed in water heated to approximately 45°C (113°F), or a hot pack should be applied, for a sustained duration. The research identifies this sustained period as ideally lasting around 45 minutes. It is important to maintain this temperature range, ensuring the water is hot but not scalding, to maximize toxin inactivation without causing injury to the patient.

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