When switching a stable patient between IV and oral Voriconazole routes, what dosage adjustment is generally maintained?
Answer
The same dose (e.g., 200 mg every 12 hours) can be maintained.
Voriconazole offers administrative flexibility, allowing for transitions between intravenous (IV) and oral dosage forms, often utilized as patients stabilize after initial therapy for systemic infections. For a patient who is clinically stable and capable of absorbing oral medication, the established dosing regimen does not necessarily require modification when switching the route of administration. Generally, the same dose, such as 200 mg administered every 12 hours, can be continued seamlessly whether delivered via IV infusion or taken orally via tablets or suspension. This consistency helps maintain steady drug levels crucial for ongoing treatment efficacy.
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