Why are brain cells uniquely vulnerable during severe hyponatremia?
Answer
They are encased in the skull, leaving no room to accommodate cellular swelling
While most cells in the body can handle a certain amount of swelling due to fluid shifts during hyponatremia, brain cells are tightly confined within the skull. This lack of space means that any expansion of brain tissue can quickly lead to severe pressure, causing symptoms like confusion, seizures, or worse.
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