Which specific immunosuppressant drug may see increased blood levels when taken concurrently with berberine?
Answer
Cyclosporine
The complex web of drug interactions involving berberine includes specific impacts on prescribed medications like immunosuppressants. Berberine has been indicated as potentially increasing the circulating blood levels of Cyclosporine. Cyclosporine is a vital drug used to prevent organ rejection in transplant recipients, and maintaining its concentration within a narrow therapeutic window is crucial for efficacy while avoiding toxicity. An elevation caused by berberine inhibition of drug clearance mechanisms requires careful management, often necessitating dose adjustments or the avoidance of the herb entirely in these patients.
Related Questions
What serious condition in infants can berberine cause by displacing bilirubin from albumin?What specific group of liver enzymes does berberine inhibit, impacting drug processing?What danger is posed to diabetics taking prescription medications if they consume barberry supplements?How long before a scheduled surgery should discontinuation of barberry use typically be recommended?Why is barberry strongly advised against for women who are breastfeeding?What impact might barberry consumption have on a person already diagnosed with hypotension?Which specific immunosuppressant drug may see increased blood levels when taken concurrently with berberine?What digestive condition might be triggered if someone with sensitivity introduces barberry supplements?How does the berberine concentration typically compare between dried barberries used sparingly in cooking versus commercial standardized supplements?When CYP enzymes are inhibited by berberine, what happens to the concentration of co-administered medications?