According to published medical literature, how do stem cells primarily mediate their effects in ASD?
Answer
Through immunomodulation and trophic factor release
Published medical findings suggest that the therapeutic impact of stem cells in conditions like ASD is generally not due to the cells physically replacing lost brain tissue. Instead, the dominant theory posits that these cells function as biological modulators. Their primary mechanism involves releasing trophic factors—substances that support cell survival and growth—and engaging in immunomodulation, which helps regulate and reduce underlying inflammatory processes believed to contribute to the pathophysiology of ASD. This mechanistic understanding implies the therapy works to correct a dysfunctional biological environment rather than achieving wholesale cellular substitution.
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What is the current clinical status of stem cell therapy for Autism Spectrum Disorder (ASD)?Which stem cell type is most frequently discussed for Autism Spectrum Disorder (ASD) treatment?What common sources are cited for the Mesenchymal Stem Cells (MSCs) administered for ASD therapy?What specific functional domains commonly show reported positive outcomes after stem cell administration for autism?Which assessment tool represents a standardized, objective metric for measuring ASD core deficits post-treatment?According to published medical literature, how do stem cells primarily mediate their effects in ASD?How is stem cell administration often framed in relation to established interventions like Applied Behavior Analysis (ABA)?What is the reported short-term safety profile for administering autologous or allogeneic MSCs?What critical element should a mandatory post-treatment plan include when evaluating a stem cell clinic checklist?What causes divergence between perceived success rates and objective clinical success rates for stem cell therapy?