How does the concentration used in commercial pesticide application of neem differ from topical skincare use?

Pesticide involves high concentration and direct environmental exposure, unlike skincare

A necessary distinction must be drawn between the varied uses of neem components, particularly concerning concentration levels and exposure routes. When neem oil is utilized commercially as an insecticide, it is formulated at high concentrations designed to be effective against pests, and the exposure is often direct and environmental, meaning contact with the substance is high. In contrast, topical skincare applications involving diluted forms, such as creams or gentle washes, focus on localized use with significantly lower concentrations intended for gentle interaction with human skin, thereby minimizing the quantity of active compounds that could potentially be systemically absorbed.