Why is Feline Idiopathic Cystitis (FIC) classified as a sterile disease by veterinarians?

Answer

No bacteria are found when the urine is cultured.

Feline Idiopathic Cystitis is termed a sterile disease because intensive testing, specifically culturing the urine sample, fails to isolate any pathogenic bacteria. This lack of microbial presence is crucial for diagnosis, as it distinguishes FIC from a typical bacterial Urinary Tract Infection (UTI). Because the underlying cause is not infectious but rather related to inflammation resulting from stress or barrier defects, administering antibiotics, which target bacteria, is typically ineffective and unwarranted unless a secondary bacterial infection is subsequently confirmed.

Why is Feline Idiopathic Cystitis (FIC) classified as a sterile disease by veterinarians?
diseaseacronymFelineurinarycystitis