What diagnostic step is essential to confirm FIC, given it is considered a diagnosis of exclusion?

Answer

Performing a urine culture to confirm the absence of bacteria.

Because Feline Idiopathic Cystitis relies on ruling out all other known causes of lower urinary tract distress, confirming the absence of bacterial infection is a mandatory step. This is achieved through a urine culture. If the culture grows no bacteria, veterinarians can confidently eliminate bacterial UTI as the cause. This methodical process of elimination—involving history, urinalysis, culture, and often imaging—is necessary before the diagnosis defaults to FIC, ensuring that treatments specific to stones or infections are not incorrectly applied to a stress-mediated inflammatory condition.

What diagnostic step is essential to confirm FIC, given it is considered a diagnosis of exclusion?
diseaseacronymFelineurinarycystitis