What protective layer lining the bladder wall is often found to be patchy or deficient in cats suffering from FIC?
Answer
Glycosaminoglycans (GAGs)
The bladder normally possesses a specialized protective barrier composed of Glycosaminoglycans (GAGs) coating the innermost lining. This GAG layer functions to shield the sensitive underlying tissue from direct contact with the concentrated, potentially irritating solutes and chemicals present in the urine. When this layer is compromised, deficient, or patchy in FIC cases, the unprotected interstitial space becomes exposed to urinary irritants, which initiates the inflammatory cascade and subsequent pain response characteristic of the condition.
Related Questions
Why is Feline Idiopathic Cystitis (FIC) classified as a sterile disease by veterinarians?What clinical sign defining urinary distress in a cat with FIC is characterized by straining to urinate?What protective layer lining the bladder wall is often found to be patchy or deficient in cats suffering from FIC?Which life-threatening complication of FIC is seen almost exclusively in male cats due to anatomical differences?What diagnostic step is essential to confirm FIC, given it is considered a diagnosis of exclusion?Which interconnected syndrome suggests that FIC involves abnormalities across multiple organ systems, particularly the nervous system?Which class of medication is prioritized during an active, non-obstructive FIC flare to manage the cat’s discomfort?What comprehensive strategy is the most impactful approach for reducing the frequency of future FIC episodes?What key dietary adjustment is emphasized as a cornerstone for chronic FIC management related to hydration?What specific numerical guideline regarding litter box quantity is advised for creating a cat-friendly habitat for FIC-prone cats?