Through which forms can localized vaginal estrogen therapy deliver hormones?
Answer
Cream, soft ring, or small tablet inserted into the vagina
Localized vaginal estrogen therapy is considered the most targeted method for addressing atrophy caused by estrogen deficiency, particularly in postmenopausal women. This therapy ensures estrogen is delivered directly to the site requiring treatment. This delivery can be achieved through several formats: a topical cream applied internally, a soft, slow-releasing ring placed inside the vagina, or a small, dissolvable tablet inserted vaginally. A key benefit of this localized approach is that the estrogen acts primarily on the surrounding tissue, resulting in minimal systemic absorption into the bloodstream compared to older, systemic hormone replacement therapies.

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