How does the addiction risk of wild lettuce compare to that of pharmaceutical opioids?
Answer
It is negligible or low
Pharmaceutical opioids are highly addictive substances because they bind to specific neurological receptors to produce potent pain relief and mood alteration. Wild lettuce, however, lacks these specific alkaloids and does not bind to these receptors, which results in a pharmacological profile with a significantly lower potential for dependence and addiction.

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Making Wild Lettuce Pain Medicine - YouTube
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