Which hormone, released by the stomach, signals the brain to initiate eating?

Answer

Ghrelin

Ghrelin is specifically identified as the 'hunger hormone' within the complex system of appetite regulation. This peptide hormone is secreted by the stomach when energy stores are perceived to be low or when food intake is due. Upon release, ghrelin travels through the bloodstream to the brain, where it signals the need to initiate the eating process, thereby stimulating appetite. This contrasts with hormones like leptin, which are secreted by fat cells to signal long-term energy storage levels and suppress appetite when those stores are sufficient.

Which hormone, released by the stomach, signals the brain to initiate eating?
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