Maintaining gut barrier integrity prevents what immunological cascade triggered by particles crossing into the bloodstream?
Answer
Triggering an immune response
A core concept linking gut health to overall systemic well-being involves the integrity of the intestinal barrier. When the gut lining is weakened, a condition sometimes referred to as leaky gut syndrome, particles that have not been fully digested or processed can inappropriately translocate across the barrier and enter the general circulation. Once these foreign or undigested components enter the bloodstream, the body's defense mechanisms recognize them as potential threats, leading to the activation of the immune system. This unnecessary activation results in an immune response, manifesting as chronic, low-grade inflammation throughout the body.
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