Which class of medications, often ending in -zide, causes forced mineral loss primarily by affecting the kidneys?
Answer
Diuretic drugs, many of which terminate with the suffix -zide, are known to significantly increase magnesium excretion through the kidneys.
A major clinical cause of forced mineral loss involves medications that influence kidney function. Diuretics, a common class used to manage fluid retention and blood pressure, often carry the suffix '-zide' (e.g., hydrochlorothiazide). These drugs function by increasing urine output, and in doing so, they cause significant renal wasting of essential minerals, including magnesium, leading to increased urinary loss and potential depletion if not managed.
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