What is the approximate time frame for naloxone onset when delivered intranasally?
Answer
Within two to three minutes
The speed of onset is dependent on the route of administration. When naloxone is delivered via the nasal spray method, which is designed for ease of use by the general public, it typically begins to take effect relatively quickly, often within a two to three minute window. If the injectable form is utilized, particularly when administered intravenously (IV), the onset can be even faster, sometimes occurring within seconds or just a minute.
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