Why should calcium and iron supplements not be taken together?

Answer

They compete for the same intestinal absorption pathways

Minerals rely on similar transporters to cross the intestinal barrier. When taken simultaneously in supplemental doses, they engage in a molecular traffic jam, competing for these limited entry points. Calcium acts as an inhibitor to non-heme iron, effectively blocking its uptake in the intestines. If these are taken together, the absorption of the iron is significantly reduced, which undermines the effectiveness of the supplementation, particularly for individuals trying to treat an iron deficiency.

Why should calcium and iron supplements not be taken together?
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