What is the primary driver of acquired discoloration, stimulating melanocytes via UV radiation?

Answer

Sun exposure

Sun exposure is recognized as perhaps the most frequent factor leading to acquired skin discoloration. The ultraviolet (UV) radiation emitted by the sun directly interacts with the skin, specifically stimulating the melanocytes—the cells responsible for synthesizing melanin. While this stimulation causes the skin to tan as a protective response, chronic or intense exposure also results in the development of specific pigmented lesions commonly labeled as sun spots, age spots, or solar lentigines. This process of pigment accumulation over time is strongly linked to cumulative sunlight dosage, particularly on areas frequently exposed like the face and hands.

What is the primary driver of acquired discoloration, stimulating melanocytes via UV radiation?
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