What active components are largely responsible for the potency of Oil of Oregano against fungi?

Answer

Carvacrol and thymol

The potent antifungal activity attributed to Oil of Oregano is directly linked to its high concentration of specific chemical markers, primarily carvacrol and, secondarily, thymol. Carvacrol is understood to interfere directly with the structural integrity of the fungal cell membranes. This interference causes leakage within the fungal cell, ultimately leading to cell death. While other agents discussed utilize different pathways, Oregano's efficacy in broad-spectrum fungal control is fundamentally tied to these two primary components.

What active components are largely responsible for the potency of Oil of Oregano against fungi?
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