How does the pathology of *D. dendriticum* generally compare to *Fasciola hepatica* concerning tissue involvement?

Answer

*D. dendriticum* tends to remain confined within the bile ducts.

A key distinction in the clinical presentation and pathology between dicrocoeliasis and infection with *Fasciola hepatica* lies in the migratory behavior of the adult worms. While *Fasciola hepatica* infection is associated with an acute systemic illness due to significant migration through the liver tissue (parenchyma), adult *Dicrocoelium dendriticum* tends to remain localized and confined within the biliary tract once they reach the liver via the portal veins. This confined nature means the resulting pathology is typically restricted to the bile ducts, manifesting as cholangitis and fibrosis, rather than widespread parenchymal damage.

How does the pathology of *D. dendriticum* generally compare to *Fasciola hepatica* concerning tissue involvement?
parasitediseaseInfectionflukedicrocoeliasis