Which congenital heart defect is historically the most significant cause associated with the term "blue baby"?
Answer
Tetralogy of Fallot (TOF)
Tetralogy of Fallot (TOF) is explicitly identified in the context as the most common and historically significant congenital heart defect associated with the moniker "blue baby." This condition involves four specific structural abnormalities occurring simultaneously. The visual symptom, cyanosis, arises because the combination of defects allows deoxygenated blood to shunt directly into the systemic circulation, bypassing the lungs, which leads to systemic hypoxemia, making TOF the central historical reference point for this clinical presentation.
Related Questions
Which congenital heart defect is historically the most significant cause associated with the term "blue baby"?What structural abnormality within Tetralogy of Fallot is described as a large hole between the two lower chambers of the heart?What physiological state is the bluish discoloration of the skin in a "blue baby" an outward manifestation of?What was the primary goal of the Blalock-Taussig (BT) shunt performed as an initial palliative approach for TOF patients?What long-term complication frequently develops in patients following a technically successful full surgical repair of TOF?What frequent, severe episodes, where the baby would become intensely cyanotic, were characteristic of life with uncorrected TOF?In TOF anatomy, what is the significance of the "overriding aorta" positioning?What crucial factor significantly impacts the prognosis for a child diagnosed with TOF in the contemporary medical era?What specific long-term factor affecting lifespan post-repair is emphasized as requiring non-negotiable follow-up adherence?What characterized the life expectancy for infants with severe TOF prior to the routine advent of modern cardiac surgery?