If an individual has a true yeast allergy, what substance in the yeast cells causes the immune reaction?
Answer
The protein content of the yeast cells
The adverse reaction associated with a genuine yeast allergy is directed specifically toward the protein components found within the yeast cells, not necessarily the live organism in its entirety. When these proteins are encountered, the immune system identifies them as harmful invaders, prompting an antibody response that leads to the release of histamine and subsequent allergic symptoms. Because the reaction is protein-based, the issue persists even after the yeast has been killed by heat during baking; the residual, denatured proteins remain present in the finished loaf, posing a potential risk to those with confirmed, severe protein allergies.

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