Chemistry articles
What polar functional groups interact favorably with water molecules increasing API solubility?
What term describes drugs that are highly water-soluble and dissolve well in water?
What challenge occurs if a drug is highly water-soluble but exhibits poor permeability?
What danger exists if a drug is not fully dissolved in an IV saline solution?
How does the highly acidic environment of the stomach (pH 1 to 3) affect a weak acid drug's water solubility?
What effect does converting a crystalline drug form into an amorphous solid have on solubility?
Which excipient technique involves forming a cage-like structure to encapsulate the drug, rendering it more soluble?
How does using a micronized powder formulation affect the dissolution of a drug compared to large crystals?
What is the primary purpose of incorporating water-miscible organic solvents like ethanol as excipients?