What biological event signals that significant height growth has stopped altogether?

Answer

The growth plates have finished their work and closed

The cessation of substantial growth is directly tied to the physical maturation of the skeletal system, specifically relating to the growth plates. When these areas of cartilage located near the ends of long bones have completed their function—multiplying and then fusing into solid bone—they are said to have closed. This closure is a marker for reaching physical maturity, signaling that the body is transitioning into its final, nearly static adult height range.

What biological event signals that significant height growth has stopped altogether?
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