What specific test is frequently utilized as the main screening tool for Growth Hormone Deficiency in children?
Answer
GH Stimulation Test
Diagnosing Growth Hormone Deficiency (GHD) often requires functional testing rather than just measuring basal GH levels, as GH secretion naturally fluctuates widely throughout the day. The GH Stimulation Test is considered the primary screening method for confirming GHD in children. This procedure involves administering specific pharmacological agents designed to stress the body and trigger the pituitary gland to release its stored GH. Subsequent blood samples are drawn at timed intervals to measure the resulting GH spike. A failure to reach a sufficient peak level after stimulation strongly indicates a functional deficiency in GH release.
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