What specialized task will pharmacists perform by translating raw genotype data in the PGx pathway?
Translating raw genotype data into phenotypic predictions like ultra-rapid metabolizer or poor metabolizer status.
The evolving role of the pharmacist positions them centrally as interpreters between raw genetic findings and practical clinical action. A genetic report provides raw genotype data (e.g., specific alleles identified). However, the clinician often needs to know the functional consequence of those alleles for drug handling—the phenotype. The pharmacist is uniquely situated to translate this molecular data into established phenotypic classifications, such as determining if a patient is a poor metabolizer, an intermediate metabolizer, or an ultra-rapid metabolizer for specific drug-metabolizing enzymes, which directly informs dosing strategies.
