What is the most effective preventative measure against local side effects like oral thrush from steroid inhalers?
Answer
Rinsing the mouth thoroughly with water and spitting it out
Inhaled corticosteroids (ICS) deposit medication locally in the oropharyngeal area, making local side effects—such as sore throat, hoarseness, or oral thrush (candidiasis)—the most common adverse effects. The single most effective action patients can take immediately following the use of their steroid inhaler to prevent these issues is rigorous oral hygiene. This involves rinsing the mouth completely with water and ensuring the rinse water is spat out, effectively washing away residual steroid particles before they can cause irritation or fungal overgrowth. If an MDI is used, employing a spacer device also aids this process by reducing initial deposition in the throat.

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